rs2290854
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7 × 10(-8), HR = 1.14, 95% CI: 1.09-1.20).
|
23544013 |
2013 |
rs2290854
|
|
A |
0.810 |
GeneticVariation |
GWASDB |
We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7 × 10(-8), HR = 1.14, 95% CI: 1.09-1.20).
|
23544013 |
2013 |
rs2290854
|
|
|
0.810 |
GeneticVariation |
BEFREE |
We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7 × 10(-8), HR = 1.14, 95% CI: 1.09-1.20).
|
23544013 |
2013 |
rs4245739
|
|
|
0.730 |
GeneticVariation |
BEFREE |
However, our study failed to show any relationship between rs4245739 A>C and rs11801299 G>A variants and BC risk (P > .05).
|
29439926 |
2018 |
rs4245739
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs.
|
29372105 |
2017 |
rs4245739
|
|
|
0.730 |
GeneticVariation |
GWASCAT |
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
|
27117709 |
2016 |
rs4245739
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Interestingly, we observed a combinational effect between MDM4 rs4245739 and P53 Arg72Pro variants in attenuating breast cancer risk, highlighting the importance of the P53 tumor suppressor pathway genes during malignant transformation.
|
23793604 |
2013 |
rs4245739
|
|
|
0.730 |
GeneticVariation |
GWASCAT |
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
23535733 |
2013 |
rs1380576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings proposed that the MDM4 rs1380576 C>G polymorphism was a protective factor for BC risk in our population.
|
29439926 |
2018 |
rs116197192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The D153G substitution only partially segregated with breast cancer in the family and was not identified on additional 680 chromosomes screened.
|
18279506 |
2008 |